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Defining the cell and molecular origins of the primate ovarian reserve

26 Aug 2025

Abstract excerpt

The primate ovarian reserve is established during late fetal development and consists of quiescent primordial follicles in the ovarian cortex each composed of granulosa cells surrounding an oocyte in dictate. As late stages of fetal development are not routinely accessible using human tissues, the current study exploits the evolutionary proximity of the rhesus macaque to investigate follicle formation in...

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PMID: 40858568
DOI: 10.1038/s41467-025-62702-0

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