Article
Genomic characterization of Burkholderia pseudomallei isolates selected for medical countermeasures testing: comparative genomics associated with differential virulence.
PloS one - 1 Jan 2015
Sahl Jason W, Allender Christopher J, Colman Rebecca E, Califf Katy J, Schupp James M, Currie Bart J, Van Zandt Kristopher E, Gelhaus H Carl, Keim Paul, Tuanyok Apichai
Abstract excerpt
Burkholderia pseudomallei is the causative agent of melioidosis and a potential bioterrorism agent. In the development of medical countermeasures against B. pseudomallei infection, the US Food and Drug Administration (FDA) animal Rule recommends using well-characterized strains in animal challenge studies. In this study, whole genome sequence data were generated for 6 B. pseudomallei isolates previously...
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