Article
ModA and ModB, two ADP-ribosyltransferases encoded by bacteriophage T4: catalytic properties and mutation analysis.
Journal of bacteriology - 1 Nov 2004
Tiemann Bernd, Depping Reinhard, Gineikiene Egle, Kaliniene Laura, Nivinskas Rimas, Rüger Wolfgang
Abstract excerpt
Bacteriophage T4 encodes three ADP-ribosyltransferases, Alt, ModA, and ModB. These enzymes participate in the regulation of the T4 replication cycle by ADP-ribosylating a defined set of host proteins. In order to obtain a better understanding of the phage-host interactions and their consequences for regulating the T4 replication cycle, we studied cloning, overexpression, and characterization of purified ModA and...
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