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Article

Molecular basis of ML-236B production in the high-producing mutant No. 41520 of Penicillium citrinum.

The Journal of general and applied microbiology - 1 Jun 2004

Abe Yuki, Baba Satoshi, Suzuki Toshihiro, Ono Chiho, Iwamoto Kohji, Hosobuchi Masahiko

Abstract excerpt

Strain improvement through random mutagenesis, screening and selection has provided us with spontaneous mutants which could produce more ML-236B than the original isolate, Penicillium citrinum SANK18767. The objective of the present study is to clarify how a high-producing mutant No. 41520 acquired the ability to produce 500 times more ML-236B than the original isolate on a molecular basis. Southern blot analysis...

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PMID: 15486826
DOI: 10.2323/jgam.50.169

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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