Article
Eleven lymphoid phenotypic markers in HIV infection: selective changes induced by zidovudine treatment.
Journal of acquired immune deficiency syndromes - 1 Jan 1992
Bass H Z, Hardy W D, Mitsuyasu R T, Wang Y X, Cumberland W, Fahey J L
Abstract excerpt
HIV infection induces substantial changes in the expression of many lymphocyte phenotypic markers as well as depletion of CD4 lymphocyte numbers. A comprehensive study was undertaken to determine whether seven lymphocyte phenotypic changes associated with HIV infection (increased CD38, HLA-DR, CD57, and CD71 and decreased CD11b, CD45RA, and leu-8) are altered by zidovudine (ZDV) administration. Levels of the four...
Topics
- Biomarkers
- HIV Infections
- Humans
- Kinetics
- Phenotype
- T-Lymphocyte Subsets
- Zidovudine
