Article
Longitudinal analysis of CD8(+) T-cell phenotype and IL-7, IL-15 and IL-16 mRNA expression in different tissues during primary simian immunodeficiency virus infection.
Microbes and infection - 1 Mar 2001
Caufour P, Le Grand R, Chéret A, Neildez O, Thiébot H, Théodoro F, Boson B, Vaslin B, Venet A, Dormont D
Abstract excerpt
Infection of macaques with pathogenic isolates of simian immunodeficiency virus (SIV) represents a useful model of HIV infection that offers the unique opportunity to investigate the very early modifications that affect CD8(+) T-lymphocyte subsets and related cytokines during lentiviral infection. Herein, three cynomolgus macaques were inoculated intravenously with a pathogenic isolate of SIVmac 251. In fresh...
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