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Article

Midline Carcinoma of Children and Young Adults With <i>NUT</i> Rearrangement

13 Oct 2004

Abstract excerpt

PURPOSE: A balanced chromosomal translocation, t(15;19), resulting in the BRD4-NUT oncogene, has been identified in a lethal carcinoma of young people, a disease described primarily in case reports. We sought to amass a more definitive series of tumors with NUT and/or BRD4 gene rearrangements and to determine distinct clinicopathologic features. PATIENTS AND METHODS: Carcinomas (N = 98) in young individuals...

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Identifiers

PMID: 15483023
DOI: 10.1200/jco.2004.02.107

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