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Article

NUTM1 Gene Fusions Characterize a Subset of Undifferentiated Soft Tissue and Visceral Tumors.

The American journal of surgical pathology - 1 May 2018

Dickson Brendan C, Sung Yun-Shao, Rosenblum Marc K, Reuter Victor E, Harb Mohammed, Wunder Jay S, Swanson David, Antonescu Cristina R

Abstract excerpt

NUT midline carcinoma is an aggressive tumor that occurs mainly in the head and neck and, less frequently, the mediastinum and lung. Following identification of an index case of a NUTM1 fusion positive undifferentiated soft tissue tumor, we interrogated additional cases of primary undifferentiated soft tissue and visceral tumors for NUTM1 abnormalities. Targeted next-generation sequencing was performed on RNA...

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Topics

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Share to Basic Helix-Loop-Helix Leucine Zipper Transcription Factors
Share to Cell Cycle Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to In Situ Hybridization, Fluorescence

Share to Neoplasm Proteins

Share to RNA-Binding Proteins

Share to Sequence Analysis, RNA

Share to Soft Tissue Neoplasms

Source

Open in PubMed Open full text

Identifiers

PMID: 29356724
DOI: 10.1097/PAS.0000000000001021
PMCID: PMC5893407

Genes

NUTM1
BCORL1
BRD3
BRD4
MXD1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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