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Article

A rare Japanese case with a NUT midline carcinoma in the nasal cavity: a case report with immunohistochemical and genetic analyses.

Pathology, research and practice - 1 Jun 2014

Suzuki Shioto, Kurabe Nobuya, Minato Hiroshi, Ohkubo Aki, Ohnishi Ippei, Tanioka Fumihiko, Sugimura Haruhiko

Abstract excerpt

BACKGROUND: NUT (nuclear protein in testis) midline carcinoma (NMC) is a recently described aggressive malignancy that is genetically defined by rearrangements of the NUT locus at 15q14. In approximately two-thirds of cases, the characteristic t(15;19) results in the fusion oncogene BRD4-NUT. Only 10 sinonasal NMCs have been documented, none of which were Japanese cases. CASE PRESENTATION: An 18-year-old woman...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 24655834
DOI: 10.1016/j.prp.2014.01.013

Genes

BRD4

Provenance

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