Article
Transcriptional reprogramming and ultrastructure during atrophy and recovery of mouse soleus muscle.
Physiological genomics - 15 Dec 2004
Däpp Christoph, Schmutz Silvia, Hoppeler Hans, Flück Martin
Abstract excerpt
This study investigated the use of the hindlimb suspension (HS) and reloading model of mice for the mapping of ultrastructural and gene expressional alterations underlying load-dependent muscular adaptations. Mice were hindlimb suspended for 7 days or kept as controls (n = 12). Soleus muscles were harvested after HS (HS7, n = 23) or after resuming ambulatory cage activity (reloading) for either 1 day (R1, n = 13)...
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