Article

Skeletal muscle fiber-type switching, myopathy, and exercise intolerance in Sigmar1 null mice

2021-04-26

Abstract excerpt

<title>Abstract</title> <p>Sigmar1 is a widely expressed, multitasking molecular chaperone protein playing functional roles in several cellular processes. Mutations in the Sigmar1 gene have been reported to associate with several motor neuropathies, including amyotrophic lateral sclerosis, distal hereditary motor neuropathy, silver-like syndrome, and frontotemporal lobar degeneration. All these human mutations as...

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Literature Corpus work: 28d5db19-b47d-5f52-8e9e-369411ee7b2d
DOI: 10.21203/rs.3.rs-399538/v1

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