Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Yeast Miro GTPase, Gem1p, regulates mitochondrial morphology via a novel pathway.

The Journal of cell biology - 11 Oct 2004

Frederick Rebecca L, McCaffery J Michael, Cunningham Kyle W, Okamoto Koji, Shaw Janet M

Abstract excerpt

Cell signaling events elicit changes in mitochondrial shape and activity. However, few mitochondrial proteins that interact with signaling pathways have been identified. Candidates include the conserved mitochondrial Rho (Miro) family of proteins, which contain two GTPase domains flanking a pair of calcium-binding EF-hand motifs. We show that Gem1p (yeast Miro; encoded by YAL048C) is a tail-anchored outer...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cytoplasm
Share to Cytoskeleton
Share to Glycerol

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to GTP Phosphohydrolases

Share to Image Processing, Computer-Assisted

Share to Intracellular Membranes

Share to Microscopy, Electron, Transmission

Share to Pheromones

Source

Open in PubMed Open full text

Identifiers

PMID: 15479738
DOI: 10.1083/jcb.200405100
PMCID: PMC2172521

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Yeast Miro GTPase, Gem1p, regulates mitochondrial morphology via a novel pathway.PMID 15479738Read ↗

Structure-function analysis of the yeast mitochondrial Rho GTPase, Gem1p: implications for mitochondrial inheritance.Semantic proximity Read ↗

Vimar Is a Novel Regulator of Mitochondrial Fission through MiroSemantic proximity Read ↗

Multiple pathways influence mitochondrial inheritance in budding yeast.Semantic proximity Read ↗

Mutations in RHOT1 Disrupt Endoplasmic Reticulum–Mitochondria Contact Sites Interfering with Calcium Homeostasis and Mitochondrial Dynamics in Parkinson's DiseaseSemantic proximity Read ↗

The Emerging Role of RHOT1/Miro1 in the Pathogenesis of Parkinson's DiseaseSemantic proximity Read ↗

VPS13D bridges the ER to Miro containing membranesSemantic proximity Read ↗

Cells lacking Pcp1p/Ugo2p, a rhomboid-like protease required for Mgm1p processing, lose mtDNA and mitochondrial structure in a Dnm1p-dependent manner, but remain competent for mitochondrial fusion.Semantic proximity Read ↗

Regulation of mitochondrial morphology and inheritance by Mdm10p, a protein of the mitochondrial outer membrane.Semantic proximity Read ↗

Mgm1p, a dynamin-related GTPase, is essential for fusion of the mitochondrial outer membrane.Semantic proximity Read ↗

The myriad roles of Miro in the nervous system: axonal transport of mitochondria and beyondSemantic proximity Read ↗

Mimicking human Drp1 disease-causing mutations in yeast Dnm1 reveals altered mitochondrial dynamics.Semantic proximity Read ↗

Emerging roles for Mitochondrial Rho GTPases in tumor biologySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.