Article
Structure-function analysis of the yeast mitochondrial Rho GTPase, Gem1p: implications for mitochondrial inheritance.
The Journal of biological chemistry - 7 Jan 2011
Koshiba Takumi, Holman Holly A, Kubara Kenji, Yasukawa Kai, Kawabata Shun-ichiro, Okamoto Koji, MacFarlane Jane, Shaw Janet M
Abstract excerpt
Mitochondria undergo continuous cycles of homotypic fusion and fission, which play an important role in controlling organelle morphology, copy number, and mitochondrial DNA maintenance. Because mitochondria cannot be generated de novo, the motility and distribution of these organelles are essential for their inheritance by daughter cells during division. Mitochondrial Rho (Miro) GTPases are outer mitochondrial...
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