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Unveiling the nexus between environmental exposures and testicular damages: revelations from autophagy and oxidative stress imbalance

29 May 2025

Abstract excerpt

Recent evidence consolidates the deleterious impact of environmental exposure on testicular damage. Environmental exposures can instigate testicular toxicity, causing damage to the Sertoli-Sertoli cell-mediated blood-testis barrier (BTB) integrity, alterations in hormone levels orchestrated by aberrant Leydig cells, and disruption of spermatogenesis. Despite diverse study designs and methodologies, a consensus is...

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PMID: 40442097
DOI: 10.1038/s41420-025-02543-4

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