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Article

Monoclonal antibodies differentially affect the interaction between the hemagglutinin of H9 influenza virus escape mutants and sialic receptors.

Virology - 10 Nov 2004

Ilyushina Natalia, Rudneva Irina, Gambaryan Alexandra, Bovin Nicolai, Kaverin Nikolai

Abstract excerpt

To determine the receptor binding properties of various H9 influenza virus escape mutants in the presence and absence of antibody, sialyloligosaccharides conjugated with biotinylated polyacrylamide were used. A mutant virus with a L226Q substitution showed an increased affinity for the Neu5Acalpha2-3Galbeta1-4Glc. Several escape mutants viruses carrying the mutation N193D bound to Neu5Acalpha2-6Galbeta1-4GlcNAc...

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Share to Antibodies, Monoclonal
Share to Antigenic Variation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Binding, Competitive

Share to Hemagglutination Inhibition Tests

Share to Hemagglutinin Glycoproteins, Influenza Virus

Share to Influenza A virus

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Source

Identifiers

PMID: 15476872
DOI: 10.1016/j.virol.2004.08.002

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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