Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

HERG channel (dys)function revealed by dynamic action potential clamp technique.

Biophysical journal - 1 Jan 2005

Berecki Géza, Zegers Jan G, Verkerk Arie O, Bhuiyan Zahurul A, de Jonge Berend, Veldkamp Marieke W, Wilders Ronald, van Ginneken Antoni C G

Abstract excerpt

The human ether-a-go-go-related gene (HERG) encodes the rapid component of the cardiac delayed rectifier potassium current (I(Kr)). Per-Arnt-Sim domain mutations of the HERG channel are linked to type 2 long-QT syndrome. We studied wild-type and/or type 2 long-QT syndrome-associated mutant (R56Q)...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biophysics
Share to Endocardium
Share to ERG1 Potassium Channel

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Ether-A-Go-Go Potassium Channels

Share to Muscle Cells

Share to Pericardium

Share to Potassium Channels, Voltage-Gated

Source

Open in PubMed Open full text

Identifiers

PMID: 15475579
DOI: 10.1529/biophysj.104.047290
PMCID: PMC1305034

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-15475579-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

HERG channel (dys)function revealed by dynamic action potential clamp technique.PMID 15475579Read ↗

The Susceptibilities of Human Ether-à-Go-Go-Related Gene Channel with the G487R Mutation to Arrhythmogenic Factors.Semantic proximity Read ↗

Comparative effects of the short QT N588K mutation at 37 degrees C on hERG K+ channel current during ventricular, Purkinje fibre and atrial action potentials: an action potential clamp study.Semantic proximity Read ↗

Long-QT syndrome-related sodium channel mutations probed by the dynamic action potential clamp technique.Semantic proximity Read ↗

hERG K(+) channels: structure, function, and clinical significance.Semantic proximity Read ↗

I(Kr): the hERG channel.Semantic proximity Read ↗

HERG, a human inward rectifier in the voltage-gated potassium channel family.Semantic proximity Read ↗

Human ether-a-go-go related gene (hERG) K+ channels: function and dysfunction.Semantic proximity Read ↗

Cardiac Delayed Rectifier Potassium Channels in Health and Disease.Semantic proximity Read ↗

The hERG K(+) channel S4 domain L532P mutation: characterization at 37°C.Semantic proximity Read ↗

A novel missense mutation causing a G487R substitution in the S2-S3 loop of human ether-à-go-go-related gene channel.Semantic proximity Read ↗

Novel characteristics of a trafficking-defective G572R-hERG channel linked to hereditary long QT syndrome.Semantic proximity Read ↗

Long QT syndrome-associated mutations in the Per-Arnt-Sim (PAS) domain of HERG potassium channels accelerate channel deactivation.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.