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Article

Induction of GABAergic phenotype in a neural stem cell line for transplantation in an excitotoxic model of Huntington's disease.

Experimental neurology - 1 Nov 2004

Bosch Miquel, Pineda José R, Suñol Cristina, Petriz Jordi, Cattaneo Elena, Alberch Jordi, Canals Josep M

Abstract excerpt

The implementation of cell replacement therapies for Huntington's disease using multipotent neural stem cells (NSCs) requires the specific differentiation into gamma-aminobutyric acid (GABA) neuronal subtype before transplantation. Here we present an efficient culture procedure that induces stable GABAergic neurons from the immortalized striatal neural stem cell line ST14A. This process requires sequential...

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PMID: 15473979
DOI: 10.1016/j.expneurol.2004.06.027

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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