Article
Homogeneity of beta(0)-thalassemia codon 17 (A-->T) alleles in Northern Thailand using a direct DNA sequencing method.
Journal of the Medical Association of Thailand = Chotmaihet thangphaet - 1 Aug 2004
Sanguansermsri Phanchana, Shimbhu Dawan, Wongvilairat Rosarin, Saetung Rattika, Sanguansermsri Torpong
Abstract excerpt
The aim of this study was to characterize beta-globin gene micro-haplotype polymorphisms (frameworks) associated with a beta-thalassemia mutations common in Northern Thailand using a direct DNA sequencing method. A total of 11 beta-thalassemia major patients homozygous for the codon 17 (A-->T) mutation admitted to Chiang Mai University Hospital were examined. All 22 alleles were found to contain the Asian...
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