Article
Molecular basis of beta thalassemia in the south of Thailand.
American journal of hematology - 1 Nov 1992
Laosombat V, Fucharoen S P, Panich V, Fucharoen G, Wongchanchailert M, Sriroongrueng W, Nopparatana C, Kenpitak K, Maipang M, Fukumaki Y
Abstract excerpt
A total of 103 beta thalassemia genes from 78 children (45 with Hb E/beta thalassemia, 8 with beta thalassemia heterozygotes, and 25 with homozygous beta thalassemia) were analyzed using dot-blot hybridization of the polymerase chain reaction-amplified DNA and direct DNA sequencing. Nine mutation...
Topics
- Alleles
- Base Sequence
- Child
- Child, Preschool
- DNA
- Globins
- Heterozygote
- Homozygote
- Humans
- Molecular Sequence Data
- Mutation
- Nucleic Acid Hybridization
- Oligonucleotide Probes
- Polymerase Chain Reaction
- Thailand
- beta-Thalassemia