Article
Molecular heterogeneity of beta-thalassemia in Thailand.
The Southeast Asian journal of tropical medicine and public health - 1 Jan 1992
Fukumaki Y, Fucharoen S, Fucharoen G, Okamoto N, Ichinose M, Jetsrisuparb A, Sriroongrueng W, Nopparatana C, Laosombat V, Panich V
Abstract excerpt
beta-Globin genes in 294 chromosomes of beta-thalassemia homozygotes and patients of beta-thalassemia/HbE in the northeast, the middle and the south of Thailand were analyzed by the PCR related techniques: dot blot hybridization, direct restriction assay, direct cloning and direct sequencing of t...
Topics
- Base Sequence
- Codon
- DNA
- DNA, Recombinant
- Gene Deletion
- Gene Frequency
- Genotype
- Globins
- Humans
- Molecular Sequence Data
- Mutation
- Phenotype
- Polymerase Chain Reaction
- Polymorphism, Genetic
- Polymorphism, Restriction Fragment Length
- Population Surveillance
- Protein Biosynthesis
- Thailand