Article
[Future perspective on the prevention of nephrolithiasis].
Hinyokika kiyo. Acta urologica Japonica - 1 Aug 2004
Kohjimoto Yasuo, Shinka Toshiaki, Morimoto Shigeyoshi, Nishihata Masaya
Abstract excerpt
Renal stone formation has been explained by the physicochemical theory; i.e., nucleation, growth and aggregation of crystals in the urine. Current medical prevention is based on this theory and seeks to modulate promoters and inhibitors of stone formation. Recent studies have identified increasing numbers of macromolecular inhibitors such as glycosaminoglycans, bikunin, osteopontin and urinary prothrombin F1....
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