Article
Urinary glycosaminoglycans as risk factors for uric acid nephrolithiasis: case control study in a Sardinian genetic isolate.
Urology - 1 Sept 2003
Ombra Maria Neve, Casula Stefania, Biino Ginevra, Maestrale Giambattista, Cardia Francesco, Melis Paola, Pirastu Mario
Abstract excerpt
OBJECTIVES: To assess the clinical association between glycosaminoglycan (GAG) excretion and uric acid (UA) nephrolithiasis by measuring urinary GAG levels in a case-control study conducted in a Sardinian genetic isolate. Inhibitors of crystallization such as GAGs seem to be involved in kidney stone formation. METHODS: Overnight (12-hour) urinary excretion of GAGs, calcium, oxalate, and UA were measured in urine...
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