Article
accordion, a zebrafish behavioral mutant, has a muscle relaxation defect due to a mutation in the ATPase Ca2+ pump SERCA1.
Development (Cambridge, England) - 1 Nov 2004
Hirata Hiromi, Saint-Amant Louis, Waterbury Julie, Cui Wilson, Zhou Weibin, Li Qin, Goldman Daniel, Granato Michael, Kuwada John Y
Abstract excerpt
When wild-type zebrafish embryos are touched at 24 hours post-fertilization (hpf), they typically perform two rapid alternating coils of the tail. By contrast, accordion (acc) mutants fail to coil their tails normally but contract the bilateral trunk muscles simultaneously to shorten the trunk, resulting in a pronounced dorsal bend. Electrophysiological recordings from muscles showed that the output from the...
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