Article
Endogenous trans-acting siRNAs regulate the accumulation of Arabidopsis mRNAs.
Molecular cell - 8 Oct 2004
Vazquez Franck, Vaucheret Hervé, Rajagopalan Ramya, Lepers Christelle, Gasciolli Virginie, Mallory Allison C, Hilbert Jean-Louis, Bartel David P, Crété Patrice
Abstract excerpt
Here we describe a set of endogenous short interfering RNAs (siRNAs) in Arabidopsis, some of which direct the cleavage of endogenous mRNAs. These siRNAs correspond to both sense and antisense strands of a noncoding RNA (At2g27400) that apparently is converted to double-stranded RNA and then processed in 21 nt increments. These siRNAs differ from previously described regulatory small RNAs in two respects. First,...
Topics
- Arabidopsis
- Arabidopsis Proteins
- Argonaute Proteins
- Base Sequence
- Cell Cycle Proteins
- Gene Expression Regulation, Plant
- MicroRNAs
- Molecular Sequence Data
- Mutation
- RNA, Messenger