Article
A link between RNA metabolism and silencing affecting Arabidopsis development.
Developmental cell - 1 Jun 2008
Gregory Brian D, O'Malley Ronan C, Lister Ryan, Urich Mark A, Tonti-Filippini Julian, Chen Huaming, Millar A Harvey, Ecker Joseph R
Abstract excerpt
MicroRNAs (miRNAs) and small interfering RNAs (siRNAs) are abundant endogenous small RNAs (smRNAs) that control transcript expression through posttranscriptional gene silencing. Here, we show that concomitant loss of XRN4/EIN5, a 5'-3' exoribonuclease, and ABH1/CBP80, a subunit of the mRNA cap binding complex, results in Arabidopsis plants manifesting myriad developmental defects. We find that ABH1/CBP80 is...
Topics
- Arabidopsis
- Arabidopsis Proteins
- Argonaute Proteins
- Exoribonucleases
- Gene Silencing
- Genes, Plant
- MicroRNAs
- Mutation
- Plant Proteins
- RNA Cap-Binding Proteins
- RNA Processing, Post-Transcriptional