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Article

Increased DNA polymerase fidelity of the Lamivudine resistant variants of human hepatitis B virus DNA polymerase.

Journal of biochemistry and molecular biology - 31 Mar 2004

Hong Young Bin, Choi Yongwook, Jung Guhung

Abstract excerpt

Although efficient antiviral lamivudine is used for HBV-infected patients, a prolonged treatment with nucleoside analogs often results in lamivudine-resistant variants. In this study, we evaluated the fidelity of the lamivudine-resistant variants. The FLAG-tagged wild-type (FPolE) and Met550 vari...

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Identifiers

PMID: 15469692
DOI: 10.5483/bmbrep.2004.37.2.167

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-15469692-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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