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Article

Functional analysis of mutations conferring lamivudine resistance on hepatitis B virus.

The Journal of general virology - 1 Mar 1999

Ling R, Harrison T J

Abstract excerpt

Two patterns of mutation are commonly observed in the polymerase gene of lamivudine [(-)2'-deoxy-3'-thiacytidine]-resistant hepatitis B virus (HBV). The M539I substitution in the conserved YMDD motif occurs independently of other changes, whereas the M539V substitution is associated with an addit...

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Source

Identifiers

PMID: 10091998
DOI: 10.1099/0022-1317-80-3-601

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-10091998-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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