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Article

Distinct Epidemiology and Clinical Consequence of Classic Versus Rare EGFR Mutations in Lung Adenocarcinoma.

Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer - 1 May 2015

Lohinai Zoltan, Hoda Mir Alireza, Fabian Katalin, Ostoros Gyula, Raso Erzsebet, Barbai Tamas, Timar Jozsef, Kovalszky Ilona, Cserepes Mihaly, Rozsas Anita, Laszlo Viktoria, Grusch Michael, Berger Walter, Klepetko Walter, Moldvay Judit, Dome Balazs, Hegedus Balazs

Abstract excerpt

INTRODUCTION: Although classic sensitizing mutations of epidermal growth factor receptor (EGFR) are positive predictive markers for EGFR tyrosine kinase inhibitors (TKIs) in lung adenocarcinoma, there are rare EGFR mutations with unknown epidemiology and influence on prognosis and TKI response. METHODS: Eight hundred and fourteen lung adenocarcinoma patients with KRAS and/or EGFR mutation analyses for TKI therapy...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 25664625
DOI: 10.1097/JTO.0000000000000492

Genes

EGFR
KRAS

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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