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High-throughput genotyping of single-nucleotide polymorphisms in ace-1 gene of mosquitoes using MALDI-TOF mass spectrometry.

Insect science - 1 Apr 2013

Mao Yun, Tan Feng, Yan Shuai-Guo, Wu Guo-Xing, Qiao Chuan-Ling, Zhang Wen-Xue, Cui Feng

Abstract excerpt

Acetylcholinesterase (AChE) plays a vital role in the nervous system of insects and other animal species and serves as the target for many chemical agents such as organophosphate and carbamate insecticides. The mosquito, Culex pipiens complex, a vector of human disease, has evolved to be resistant to insecticides by a limited number of amino acid substitutions in AChE1, which is encoded by the ace-1 gene. The...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 23955857
DOI: 10.1111/j.1744-7917.2012.01520.x

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