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Article

A proteomic approach to study msDNA function in Escherichia coli.

Journal of microbiology (Seoul, Korea) - 1 Sept 2004

Jeong Mi-Ae, Lim Dongbin

Abstract excerpt

Retron is a prokaryotic genetic element that produces multicopy single-stranded DNA covalently linked to RNA (msDNA) by a reverse transcriptase. It was found that cells producing a large amount of msDNA, rather than those that did not, showed a higher rate of mutation. In order to understand the molecular mechanism connecting msDNA production to the high mutation rate the protein patterns were compared by two...

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PMID: 15459648

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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