Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The receptor tyrosine kinase Off-track is required for layer-specific neuronal connectivity in Drosophila.

Development (Cambridge, England) - 1 Nov 2004

Cafferty Patrick, Yu Li, Rao Yong

Abstract excerpt

The nervous system in many species consists of multiple neuronal cell layers, each forming specific connections with neurons in other layers or other regions of the brain. How layer-specific connectivity is established during development remains largely unknown. In the Drosophila adult visual system, photoreceptor (R cell) axons innervate one of two optic ganglia layers; R1-R6 axons connect to the lamina layer,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Axons
Share to Body Patterning
Share to Cell Lineage

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Growth Cones

Share to Neuroglia

Share to Receptor Protein-Tyrosine Kinases

Share to Semaphorins

Source

Identifiers

PMID: 15456725
DOI: 10.1242/dev.01406

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The receptor tyrosine kinase Off-track is required for layer-specific neuronal connectivity in Drosophila.PMID 15456725Read ↗

Retinal axon target selection in Drosophila is regulated by a receptor protein tyrosine phosphatase.Semantic proximity Read ↗

Flamingo regulates R8 axon-axon and axon-target interactions in the Drosophila visual system.Semantic proximity Read ↗

Gogo receptor contributes to retinotopic map formation and prevents R1-6 photoreceptor axon bundling.Semantic proximity Read ↗

The protocadherin Flamingo is required for axon target selection in the Drosophila visual system.Semantic proximity Read ↗

Drosophila N-cadherin functions in the first stage of the two-stage layer-selection process of R7 photoreceptor afferents.Semantic proximity Read ↗

Drosophila LAR regulates R1-R6 and R7 target specificity in the visual system.Semantic proximity Read ↗

The transmembrane protein Off-track associates with Plexins and functions downstream of Semaphorin signaling during axon guidance.Semantic proximity Read ↗

Guidance-cue control of horizontal cell morphology, lamination, and synapse formation in the mammalian outer retina.Semantic proximity Read ↗

DWnt4 regulates the dorsoventral specificity of retinal projections in the Drosophila melanogaster visual system.Semantic proximity Read ↗

Analysis of Drosophila photoreceptor axon guidance in eye-specific mosaics.Semantic proximity Read ↗

Orthodenticle Is Required for the Expression of Principal Recognition Molecules That Control Axon Targeting in the Drosophila Retina.Semantic proximity Read ↗

Afferent growth cone interactions control synaptic specificity in the Drosophila visual system.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.