A vaccinia serine protease inhibitor which prevents virus-induced cell fusion.

doi:10.1099/0022-1317-73-3-549

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Article

A vaccinia serine protease inhibitor which prevents virus-induced cell fusion.

The Journal of general virology - 1 Mar 1992

Law K M, Smith G L

Abstract excerpt

A deletion mutant lacking the non-essential vaccinia virus gene K2L, a member of the serine protease inhibitor superfamily, was constructed. This virus replicates in vitro in all cell types tested and its virulence and immunogenicity in vivo are comparable to those of the parent virus in intranas...

Topics

Cell Fusion
Chromosome Mapping
Genes, Viral
Mutagenesis
Mutation
Serpins
Vaccinia
Vaccinia virus
Viral Fusion Proteins
Virulence
Virus Replication

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