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Article

A vaccinia serine protease inhibitor which prevents virus-induced cell fusion.

The Journal of general virology - 1 Mar 1992

Law K M, Smith G L

Abstract excerpt

A deletion mutant lacking the non-essential vaccinia virus gene K2L, a member of the serine protease inhibitor superfamily, was constructed. This virus replicates in vitro in all cell types tested and its virulence and immunogenicity in vivo are comparable to those of the parent virus in intranasally inoculated mice. However, in a variety of cell lines the cytopathic effect of the deletion mutant (vKL4) is...

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Identifiers

PMID: 1545218
DOI: 10.1099/0022-1317-73-3-549

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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