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Article

FGF6 mediated expansion of a resident subset of cells with SP phenotype in the C2C12 myogenic line.

Journal of cellular physiology - 1 Dec 2004

Israeli David, Benchaouir Rachid, Ziaei Simindokht, Rameau Philippe, Gruszczynski Carole, Peltekian Elise, Danos Olivier, Garcia Luis

Abstract excerpt

Fibroblast growth factor 6 (FGF6) is selectively expressed during muscle development and regeneration. We examined its effect on muscle precursor cells (mpc) by forcing stable FGF6 expression in C2C12 cells in vitro. FGF6 produced in genetically engineered mpc was active, inducing strong morphological changes, altering cell adhesion and compromising their ability to differentiate into myotubes. Expression of MyoD...

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Source

Identifiers

PMID: 15389547
DOI: 10.1002/jcp.20088

Genes

FGF6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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