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Article

Apo-azurin folds via an intermediate that resembles the molten-globule.

Protein science : a publication of the Protein Society - 1 Oct 2004

Sandberg Anders, Leckner Johan, Karlsson B Göran

Abstract excerpt

The folding of Pseudomonas aeruginosa apo-azurin was investigated with the intent of identifying putative intermediates. Two apo-mutants were constructed by replacing the main metal-binding ligand C112 with a serine (C112S) and an alanine (C112A). The guanidinium-induced unfolding free energies (DeltaG(U-N)(H2O)) of the C112S and C112A mutants were measured to 36.8 +/- 1 kJ mole(-1) and 26.1 +/- 1 kJ mole(-1),...

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Source

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Identifiers

PMID: 15388858
DOI: 10.1110/ps.04848204
PMCID: PMC2286560

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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