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Article

Phi-value analysis of apo-azurin folding: comparison between experiment and theory.

Biochemistry - 23 May 2006

Zong Chenghang, Wilson Corey J, Shen Tongye, Wolynes Peter G, Wittung-Stafshede Pernilla

Abstract excerpt

Pseudomonas aeruginosa azurin is a 128-residue beta-sandwich metalloprotein; in vitro kinetic experiments have shown that it folds in a two-state reaction. Here, we used a variational free energy functional to calculate the characteristics of the transition state ensemble (TSE) for folding of the apo-form of P. aeruginosa azurin and investigate how it responds to thermal and mutational changes. The variational...

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Identifiers

PMID: 16700556
DOI: 10.1021/bi060025w

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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