Article
Regulatory roles for the homeodomain and C2H2 zinc finger regions of Cryptococcus neoformans Ste12alphap.
Molecular microbiology - 1 Sept 2004
Chang Yun C, Wright L C, Tscharke R L, Sorrell T C, Wilson C F, Kwon-Chung K J
Abstract excerpt
The STE12alpha gene of Cryptococcus neoformans encodes a protein containing both homeodomain and zinc finger regions. As homeodomains and zinc finger regions are important domains for the function of many transcription factors, we used site-specific mutagenesis to delineate the roles of these two domains. The homeodomain and zinc finger regions are each important for the function of Ste12alphap. DNA binding...
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