Article
Cryptococcus neoformans STE12alpha regulates virulence but is not essential for mating.
The Journal of experimental medicine - 6 Mar 2000
Chang Y C, Wickes B L, Miller G F, Penoyer L A, Kwon-Chung K J
Abstract excerpt
The Cryptococcus neoformans STE12alpha gene, a homologue of Saccharomyces cerevisiae STE12, exists only in mating type (MAT)alpha cells. In S. cerevisiae, STE12 was required for mating and filament formation. In C. neoformans, haploid fruiting on filament agar required STE12alpha. The ability to form hyphae, however, was not affected by deletion of STE12alpha when convergently growing MATa strains were present....
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