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Article

The second STE12 homologue of Cryptococcus neoformans is MATa-specific and plays an important role in virulence.

Proceedings of the National Academy of Sciences of the United States of America - 13 Mar 2001

Chang Y C, Penoyer L A, Kwon-Chung K J

Abstract excerpt

Cryptococcus neoformans STE12alpha, a homologue of Saccharomyces cerevisiae STE12, exists only in MATalpha strains. We identified another STE12 homologue, STE12a, which is MATa specific. As in the case with Deltaste12alpha, the mating efficiency for Deltaste12a was reduced significantly. The Delt...

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Identifiers

PMID: 11248066
DOI: 10.1073/pnas.061031998
PMCID: PMC30641

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-11248066-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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