Article
Association of the gene encoding wingless-type mammary tumor virus integration-site family member 5B (WNT5B) with type 2 diabetes.
American journal of human genetics - 1 Nov 2004
Kanazawa Akio, Tsukada Syuuichi, Sekine Akihiro, Tsunoda Tatsuhiko, Takahashi Atsushi, Kashiwagi Atsunori, Tanaka Yasushi, Babazono Tetsuya, Matsuda Masafumi, Kaku Kohei, Iwamoto Yasuhiko, Kawamori Ryuzo, Kikkawa Ryuichi, Nakamura Yusuke, Maeda Shiro
Abstract excerpt
Recent reports have suggested that WNT signaling is an important regulator for adipogenesis or insulin secretion and might be involved in the pathogenesis of type 2 diabetes. To investigate possible roles of the WNT genes in conferring susceptibility to type 2 diabetes, we examined the association of the genes that encode members of the WNT family with type 2 diabetes in the Japanese population. First, 40...
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