Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic variations in the gene encoding TFAP2B are associated with type 2 diabetes mellitus.

Journal of human genetics - 1 Jan 2005

Maeda Shiro, Tsukada Shuichi, Kanazawa Akio, Sekine Akihiro, Tsunoda Tatsuhiko, Koya Daisuke, Maegawa Hiroshi, Kashiwagi Atsunori, Babazono Tetsuya, Matsuda Masafumi, Tanaka Yasushi, Fujioka Tomoaki, Hirose Hiroshi, Eguchi Takashi, Ohno Yoichi, Groves Christopher J, Hattersley Andrew T, Hitman Graham A, Walker Mark, Kaku Kohei, Iwamoto Yasuhiko, Kawamori Ryuzo, Kikkawa Ryuichi, Kamatani Naoyuki, McCarthy Mark I, Nakamura Yusuke

Abstract excerpt

To search a gene(s) conferring susceptibility to type 2 diabetes mellitus, we genotyped nearly 60,000 gene-based SNPs for Japanese patients and found evidence that the gene at chromosome 6p12 encoding transcription-factor-activating protein 2beta (TFAP2B) was a likely candidate in view of signifi...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Diabetes Mellitus, Type 2
Share to Japan

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Linkage Disequilibrium

Share to Odds Ratio

Share to Regression Analysis

Share to Reverse Transcriptase Polymerase Chain Reaction

Share to Transcription Factor AP-2

Share to United Kingdom

Source

Identifiers

PMID: 15940393
DOI: 10.1007/s10038-005-0253-9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-15940393-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic variations in the gene encoding TFAP2B are associated with type 2 diabetes mellitus.PMID 15940393Read ↗

Intronic Polymorphisms within TFAP2B Regulate Transcriptional Activity and Affect Adipocytokine Gene Expression in Differentiated AdipocytesSemantic proximity Read ↗

Genome-wide association studies in the Japanese population identify seven novel loci for type 2 diabetes.Semantic proximity Read ↗

In silico functional and pathway analysis of risk genes and SNPs for type 2 diabetes in Asian population.Semantic proximity Read ↗

Genetic variants on chromosome 6p21.1 and 6p22.3 are associated with type 2 diabetes risk: a case-control study in Han Chinese.Semantic proximity Read ↗

A 212-kb region on chromosome 6q25 containing the TAB2 gene is associated with susceptibility to type 1 diabetes.Semantic proximity Read ↗

Replication of genome-wide association studies of type 2 diabetes susceptibility in Japan.Semantic proximity Read ↗

Functional annotation of sixty-five type-2 diabetes risk SNPs and its application in risk prediction.Semantic proximity Read ↗

Association of CDKAL1, IGF2BP2, CDKN2A/B, HHEX, SLC30A8, and KCNJ11 with susceptibility to type 2 diabetes in a Japanese population.Semantic proximity Read ↗

Comprehensive association study of type 2 diabetes and related quantitative traits with 222 candidate genes.Semantic proximity Read ↗

A comparative analysis of genetic diversity of candidate genes associated with type 2 diabetes in worldwide populations.Semantic proximity Read ↗

Association between FABP2 Ala54Thr polymorphisms and type 2 diabetes mellitus risk: a HuGE Review and Meta-Analysis.Semantic proximity Read ↗

Association between type 2 diabetes and CDKN2A/B: a meta-analysis study.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.