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Article

Pseudomonas aeruginosa relA contributes to virulence in Drosophila melanogaster.

Infection and immunity - 1 Oct 2004

Erickson David L, Lines J Louise, Pesci Everett C, Venturi Vittorio, Storey Douglas G

Abstract excerpt

The stringent response is a mechanism by which bacteria adapt to nutritional deficiencies through the production of the guanine nucleotides ppGpp and pppGpp, produced by the RelA enzyme. We investigated the role of the relA gene in the ability of an extracellular pathogen, Pseudomonas aeruginosa, to cause infection. Strains lacking the relA gene were created from the prototypical laboratory strain PAO1 as well as...

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Identifiers

PMID: 15385461
DOI: 10.1128/IAI.72.10.5638-5645.2004
PMCID: PMC517598

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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