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Article

SOX9 is up-regulated by the transient expression of SRY specifically in Sertoli cell precursors.

Developmental biology - 15 Oct 2004

Sekido Ryohei, Bar Isabelle, Narváez Véronica, Penny Graeme, Lovell-Badge Robin

Abstract excerpt

The Y chromosome gene Sry encodes a transcription factor required to initiate testis development. The related autosomal gene Sox9 is up-regulated shortly after the onset of Sry transcription and is thought essential for the differentiation of Sertoli cells. The lineage that gives rise to Sertoli cells has its origins within the coelomic epithelium (CE) of the genital ridge, but from cells also able to give rise...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 15385158
DOI: 10.1016/j.ydbio.2004.07.011

Genes

SRY
SOX9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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SOX9 is up-regulated by the transient expression of SRY specifically in Sertoli cell precursors.PMID 15385158Read ↗

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