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Article

No major association between TGFBR1*6A and prostate cancer.

BMC genetics - 22 Sept 2004

Kaklamani Virginia, Baddi Lisa, Rosman Diana, Liu Junjian, Ellis Nathan, Oddoux Carole, Ostrer Harry, Chen Yu, Ahsan Habibul, Offit Kenneth, Pasche Boris

Abstract excerpt

Prostate cancer is the most commonly diagnosed cancer in men and one of the leading causes of cancer deaths. There is strong genetic evidence indicating that a large proportion of prostate cancers are caused by heritable factors but the search for prostate cancer susceptibility genes has thus far remained elusive. TGFBR1*6A, a common hypomorphic variant of the type I Transforming Growth Factor Beta receptor, is...

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Source

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Identifiers

PMID: 15385056
DOI: 10.1186/1471-2156-5-28
PMCID: PMC521683

Genes

TGFBR1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

No major association between TGFBR1*6A and prostate cancer.PMID 15385056Read ↗

TGFBR1*6A is not associated with prostate cancer in men of European ancestry.Semantic proximity Read ↗

TGFBR1*6A and cancer risk: a meta-analysis of seven case-control studies.Semantic proximity Read ↗

The TGFBR1*6A/9A polymorphism is not associated with differential risk of breast cancer.Semantic proximity Read ↗

TGFBR1*6A/9A polymorphism and cancer risk: a meta-analysis of 13,662 cases and 14,147 controls.Semantic proximity Read ↗

Lack of an association between the TGFBR1*6A variant and colorectal cancer risk.Semantic proximity Read ↗

No association between TGFBR1*6A and lung cancer.Semantic proximity Read ↗

TGFBR1*6A and cancer: a meta-analysis of 12 case-control studies.Semantic proximity Read ↗

TGFBR1 variants TGFBR1(*)6A and Int7G24A are not associated with an increased familial colorectal cancer risk.Semantic proximity Read ↗

Lack of association of transforming growth factor-beta1 polymorphisms and haplotypes with prostate cancer risk in the prostate, lung, colorectal, and ovarian trial.Semantic proximity Read ↗

TGFBR1*6A as a modifier of breast cancer risk and progression: advances and future prospectsSemantic proximity Read ↗

Interleukin-6 sequence variants are not associated with prostate cancer risk.Semantic proximity Read ↗

A gain of function TGFB1 polymorphism may be associated with late stage prostate cancer.Semantic proximity Read ↗

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