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Article

TAU mutations are not a predominant cause of frontotemporal dementia in Canadian patients.

The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques - 1 Aug 2004

Levchenko Anastasia, Robitaille Yves, Strong Michael J, Rouleau Guy A

Abstract excerpt

OBJECTIVE: Frontotemporal dementia is a neurodegenerative disease affecting mostly the frontal and/or temporal lobes, with neuronal loss and intraneuronal and/or intraglial inclusions composed of hyperphosphorylated microtubule-associated protein tau and ubiquitin. Missense and splice site mutations in the TAU gene have been identified in approximately 15% of all frontotemporal dementia cases. In this study, we...

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Identifiers

PMID: 15376481
DOI: 10.1017/s0317167100003450

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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