Article
Association analyses of DNA methyltransferase-1 (DNMT1) polymorphisms with systemic lupus erythematosus.
Journal of human genetics - 1 Jan 2004
Park Byung Lae, Kim Lyoung Hyo, Shin Hyoung Doo, Park Yong Wook, Uhm Wan Sik, Bae Sang-Cheol
Abstract excerpt
The etiology of systemic lupus erythematosus (SLE) is very complex, and genetic factors appear to play a significant role in susceptibility to SLE, in determining the disease expression, and in the autoantibody profiles of individuals with SLE. DNA methyltransferase-1 (DNMT1) is a major enzyme th...
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