Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The human <i>BCL6</i> transgene promotes the development of lymphomas in the mouse

16 Sept 2004

Abstract excerpt

BCL6, a gene on chromosome 3, band q27, encodes a zinc finger transcriptional repressor that is needed for germinal center formation and has been implicated in the pathogenesis of some human lymphomas when it is mutated or involved in chromosomal rearrangements. To explore further the mechanisms of action of BCL6 in lymphomagenesis, we developed a transgenic mouse model mimicking a common translocation, the t(3,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to CAR-T cell therapy research
Share to Chronic Lymphocytic Leukemia Research
Share to Lymphoma Diagnosis and Treatment

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 15375218
DOI: 10.1073/pnas.0406138101

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The human <i>BCL6</i> transgene promotes the development of lymphomas in the mousePMID 15375218Read ↗

The proto-oncogene BCL-6 in normal and malignant B cell development.Semantic proximity Read ↗

Transient expression of Bcl6 is sufficient for oncogenic function and induction of mature B-cell lymphoma.Semantic proximity Read ↗

<i>PIM1</i> gene cooperates with human <i>BCL6</i> gene to promote the development of lymphomasSemantic proximity Read ↗

Animal models for chronic lymphocytic leukemiaSemantic proximity Read ↗

Dysregulated TCL1 promotes multiple classes of mature B cell lymphomaSemantic proximity Read ↗

Mouse Models of Germinal Center Derived B-Cell Lymphomas.Semantic proximity Read ↗

The BCL6 proto-oncogene: a leading role during germinal center development and lymphomagenesisSemantic proximity Read ↗

Mouse Models in the Study of Mature B-Cell Malignancies.Semantic proximity Read ↗

Eμ-BRD2 transgenic mice develop B-cell lymphoma and leukemiaSemantic proximity Read ↗

Roles of BCL6 in normal and transformed germinal center B cellsSemantic proximity Read ↗

Mechanisms of action of BCL6 during germinal center B cell developmentSemantic proximity Read ↗

Human B Lymphomas Reveal Their Secrets Through Genetic Mouse Models.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.