Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Nuclear Factor-κB is an Important Modulator of the Altered Gene Expression Profile and Malignant Phenotype in Squamous Cell Carcinoma

15 Sept 2004

Abstract excerpt

We reported previously that transcription factor nuclear factor (NF)-kappaB is constitutively activated in human and murine squamous cell carcinomas (SCCs). The role of NF-kappaB in the cumulative changes in gene expression with transformation and progression of the murine SCC Pam 212 and after switching off NF-kappaB by a dominant negative inhibitor kappaB mutant (IkappaBalphaM) was explored by profiling with a...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cytokine Signaling Pathways and Interactions
Share to Natural product bioactivities and synthesis
Share to NF-κB Signaling Pathways

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 15374962
DOI: 10.1158/0008-5472.can-04-0852

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Nuclear Factor-κB is an Important Modulator of the Altered Gene Expression Profile and Malignant Phenotype in Squamous Cell CarcinomaPMID 15374962Read ↗

Head and Neck Cancers Promote an Inflammatory Transcriptome through Coactivation of Classic and Alternative NF-κB PathwaysSemantic proximity Read ↗

The role of NF-kappaB/IkappaB proteins in cancer: implications for novel treatment strategies.Semantic proximity Read ↗

Nuclear Factor-κB Activation: From Bench to BedsideSemantic proximity Read ↗

NF-κB signaling in neoplastic transition from epithelial to mesenchymal phenotype.Semantic proximity Read ↗

Nuclear Factor κB Signaling and Its Related Non-coding RNAs in Cancer TherapySemantic proximity Read ↗

Transcriptional Regulation during Aberrant Activation of NF-κB Signalling in CancerSemantic proximity Read ↗

Subunit-Specific Role of NF-κB in CancerSemantic proximity Read ↗

NF-kappaB and epithelial to mesenchymal transition of cancer.Semantic proximity Read ↗

Nuclear Factor-κB in Development, Prevention, and Therapy of CancerSemantic proximity Read ↗

Links between alpha-catenin, NF-kappaB, and squamous cell carcinoma in skin.Semantic proximity Read ↗

NF-κB signaling pathway and its potential as a target for therapy in lymphoid neoplasms.Semantic proximity Read ↗

NF‐κB activation in development and progression of cancerSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.