Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Upstream stimulatory factors regulate the C/EBP alpha gene during differentiation of 3T3-L1 preadipocytes.

Biochemical and biophysical research communications - 9 Mar 2007

Kim Jae-woo, Monila Henrik, Pandey Akhilesh, Lane M Daniel

Abstract excerpt

During adipocyte differentiation, CCAAT/enhancer-binding protein alpha (C/EBPalpha) functions as a pleiotropic transcriptional activator of numerous adipocyte genes. The promoter of the C/EBPalpha gene has an E-box upstream of C/EBP binding site. Deletion or mutation of the E-box decreases promoter activity, suggesting that the E-box participates in the regulation of C/EBPalpha expression. Protein binding to the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to 3T3-L1 Cells
Share to Adipocytes
Share to CCAAT-Enhancer-Binding Protein-alpha

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Cell Differentiation

Share to Gene Expression Regulation

Share to Repressor Proteins

Share to Stem Cells

Share to Upstream Stimulatory Factors

Source

Identifiers

PMID: 17239350
DOI: 10.1016/j.bbrc.2007.01.008

Genes

EBP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Upstream stimulatory factors regulate the C/EBP alpha gene during differentiation of 3T3-L1 preadipocytes.PMID 17239350Read ↗

Role of the CCAAT Enhancer Binding Proteins (C/EBPs) in Adipocyte DifferentiationSemantic proximity Read ↗

Cloning and transcriptional regulation of a novel adipocyte-specific gene, FSP27. CAAT-enhancer-binding protein (C/EBP) and C/EBP-like proteins interact with sequences required for differentiation-dependent expression.Semantic proximity Read ↗

Sequential gene promoter interactions of C/EBPbeta, C/EBPalpha, and PPARgamma during adipogenesis.Semantic proximity Read ↗

Transcriptional Regulation of Adipocyte Differentiation: A Central Role for CCAAT/Enhancer-binding Protein (C/EBP) βSemantic proximity Read ↗

Temporal recruitment of CCAAT/enhancer-binding proteins to early and late adipogenic promoters in vivoSemantic proximity Read ↗

CCAAT/enhancer binding protein gene promoter: binding of nuclear factors during differentiation of 3T3-L1 preadipocytes.Semantic proximity Read ↗

p300-Dependent Acetylation of Activating Transcription Factor 5 Enhances C/EBPβ Transactivation of C/EBPα during 3T3-L1 DifferentiationSemantic proximity Read ↗

Cooperation between C/EBPalpha TBP/TFIIB and SWI/SNF recruiting domains is required for adipocyte differentiation.Semantic proximity Read ↗

p300 Coactivates the Adipogenic Transcription Factor CCAAT/Enhancer-binding Protein αSemantic proximity Read ↗

Analysis of a tissue-specific enhancer: ARF6 regulates adipogenic gene expression.Semantic proximity Read ↗

Repressive Effect of Sp1 on the C/EBPα Gene Promoter: Role in Adipocyte DifferentiationSemantic proximity Read ↗

Upstream stimulatory factors regulate aortic preferentially expressed gene-1 expression in vascular smooth muscle cells.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.