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Article

Novel CYP2C9 genetic variants in Asian subjects and their influence on maintenance warfarin dose.

Clinical pharmacology and therapeutics - 1 Sept 2004

Zhao Feng, Loke Celine, Rankin Sheila Clare, Guo Jia-Yi, Lee How Sung, Wu Tuck Seng, Tan Theresa, Liu Te-Chih, Lu Wan-Liang, Lim Yean-Teng, Zhang Qiang, Goh Boon Cher, Lee Soo Chin

Abstract excerpt

BACKGROUND: Commonly occurring genetic variants in CYP2C9 are known to reduce catalytic activity and are associated with enhanced patient sensitivity to warfarin. Interethnic differences in warfarin dose requirement have been described in the Asian population, and we postulate that this could be related to genetic variants of CYP2C9 that are unique to ethnic groups. METHODS: We prospectively genotyped 125...

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Identifiers

PMID: 15371982
DOI: 10.1016/j.clpt.2004.05.005

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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