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Article

Gaucher cells demonstrate a distinct macrophage phenotype and resemble alternatively activated macrophages.

American journal of clinical pathology - 1 Sept 2004

Boven Leonie A, van Meurs Marjan, Boot Rolf G, Mehta Atul, Boon Louis, Aerts Johannes M, Laman Jon D

Abstract excerpt

Although the existence of anti-inflammatory alternatively activated macrophages (aamphi) has been accepted widely based on in vitro studies, their in vivo location, phenotype, and function still are debated. Gaucher disease (GD) is caused by a genetic deficiency in the lysosomal enzyme glucocerebrosidase and is characterized by accumulation of glycosphingolipids in so-called Gaucher cells (GCs). By using...

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Identifiers

PMID: 15362365
DOI: 10.1309/BG5V-A8JR-DQH1-M7HN

Genes

CCL18

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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